Case Studies

  • First-of-a-Kind Liposuction System

    MPR was asked by a start-up company with an innovative core technology to develop the Phaser Lipoplasty System, to allow for more effective tissue removal during liposuction procedures. By identifying and employing specific pressures and temperatures, adipose tissue may be removed with this system without burning or otherwise damaging non-target tissues within the surgical field. MPR performed initial testing to characterize this technology, as well as conceptualization, proof-of-concept development, detailed engineering, and verification and validation activities. By working concurrently with our industrial design service, HUCKdesign℠, the new liposuction system was delivered from sketch to FDA submission in twelve months. The device has now been cleared by the FDA. Read More

  • Cell Isolation Technology

    An MPR client desired to manufacture a medical device to isolate adiposederived adult stem cells (endothelial cells). A form of human primary cell, endothelial cells are used in a wide range of laboratory activities, from the creation of new therapies addressing human diseases to the healing of wounds and treatment of burns. Traditionally, isolating these cells from other components of human tissue has been a complex process, requiring timeconsuming and expensive human intervention with a manual, multi-step and inconsistent methodology. Read More

  • Periodontal Ultrasonic Imaging System

    A start-up company in the dental industry wanted to take a new concept for a digital imaging and diagnostic device for non-invasively detecting and monitoring treatment of periodontal disease, from a university laboratory environment to the clinical practice setting. Read More

  • Radiopharmaceutical Synthesis Device

    A leading supplier of products for radioisotope detection and analysis in life science, pharmaceutical and nuclear medicine research applications challenged MPR to design a new system for the labeling of Positron Emission Tomography (PET) tracers, including C-11 methylations and F-18 fluoroalkylations. The product needed to follow the client's flexible product strategy, be easy to use, maintain and clean, cost and reagent efficient, and consistent in product yield - all areas of concern with other C-11 radiopharmaceutical systems that typically have been manually prepared. Read More

  • Production Process Case - MPR Assists Drug Manufacturer in Designing Delivery Device, Production Process, and Manufacturing Facility

    A specialty pharmaceutical company sought to develop a first-of-a-kind drug delivery device, and design and rapidly construct a manufacturing facility for the combination product. However, the traditional facility build-out approach using process engineering, architect, builder, and validation firms creates schedule risk due to the various organizational interfaces. To manage this risk and complete the project on a very aggressive timeline, the company engaged MPR to provide the overall leadership, project management, and owner's engineering services. Read More

  • Combination Device: From Development to Production

    A start-up pharmaceutical manufacturer was planning the development of a production facility for a new combination drug-device product. The nature of the product and needs of the marketplace required a first-of-a-kind sterile manufacturing process and an aggressive timeline, both key project challenges. Read More

  • First-of-its-Kind Proteomics Device and Disposable Microplate

    A life sciences company sought to leverage expertise in imaging mass spectrometry (IMS) to enable pharmaceutical and biotech customers to gain new, important insights into disease progression, drug treatment and metabolic response. The company's goal was to rapidly transfer a conceptualized proteomics laboratory device into a commercially viable bench-top instrument, capable of simultaneously and independently processing 96 mechanically and electrically isolated samples contained within disposable sample cartridges. Read More

  • Convertible Chemical Synthesis System

    In order to accelerate time to market and decrease production and service costs, MPR designed a new convertible chemical synthesis system satisfying the technical needs of two devices simultaneously. The automated chemistry module can be used with both positron emission tomography (PET) or in the production of Fluorodeoxyglucose (FDG) for use in diagnostic imaging. HUCKdesign℠, a service of MPR's Product Development Group, provided the industrial design expertise for the unit. The presence of extremely aggressive chemicals prevented the use of most commercial finishes resulting in the use of anodized brushed aluminum and polished stainless steel exterior panels. The installation of the disposable components was carefully assessed and supported by graphic traces and informative copy created by HUCKdesign℠. Supervision of prototype fabrication and assembly were provided as part of a comprehensive industrial design plan, with the device being ready for market in less than eight months. Read More

  • Gel Protein Recovery System

    MPR developed the GPR-800 to function as a gel protein recovery system. MPR performed all phases of the product development process from performing detailed engineering of the microchip-based protein/peptide processing system to the industrial design of the enclosure. The case of the device was designed to convey a professional image both distinctive and relevant to the universe of cutting edge laboratory technology. The MPR Product Development team created the development platform for the GPR-800 along with the alpha prototype. The time from project kick-off to delivery of production units was eight months. Read More