• How To Spend Your First $100,000

    Imagine you are an early stage entrepreneur with a breakthrough technology, some promising intellectual property, and $100K is on the way from a new investor. What do you need to do to maximize your chances of success? Early stage device start ups are more likely to gain access to seed capital rather than a large investment, but they often have a problem figuring out how to spend the money in a way that will lead to more funding. Read More

  • Wind Energy in Mexico: Development and Execution Best Practices

    Development of wind projects in Mexico presents several challenges and opportunities that are unique to the Mexican marketplace. High PPA tariffs and a growing energy market attract developers to the Mexican wind market. However, seizing these opportunities requires developers to understand the needs of stakeholders such as Off-takers, CRE (Energy Regulatory Commission), and CFE (State Owned Utility). Some of the critical development challenges include: identifying viable Points of Interconnection, securing PPA's, working with limited small scale wind data, and managing the substation engineering design, review, and approval process. During the construction phase, some of the important challenges include: major equipment importation, EPC planning and reporting, and site safety, security and theft. Lastly, it is important to appreciate the positive influence of the Spanish workforce during Wind Turbine Generator (WTG) installation and the support from CFE during substation testing and start-up. Read More

  • Continuous Blood Glucose Monitor

    An MPR client desired a medical device capable of automated glucose monitoring using a conventional in-line intravascular (IV) catheter. The device was to be designed specifically for patients undergoing intensive insulin therapy in critical and intensive care units. It was required that the monitoring system would automatically sample the patient's blood, test the blood for glucose levels, and reinfuse the blood into the patient, ensuring the entire fluid pathway was kept clean for extended periods of time (up to our days). In addition, the device was required to operate in an automatic unattended fashion and report any abnormal readings. Read More

  • Energy White Paper: Technical Overview of Carbon Dioxide Sequestration Technologies

    Atmospheric levels of carbon dioxide (CO2) have increased from a pre-industrial level of 280 parts-per-million (ppm) to today's level of 379 ppm [Reference 2]. The primary source of anthropogenic CO2 is combustion of fossil fuels. Studies have shown that capture of anthropogenic CO2 and carbon sequestration could help to stabilize the concentration of atmospheric CO2. This paper investigates the leading methods for carbon sequestration and evaluates them on the bases of cost, capacity and environmental consequences. Other factors such as geographical constraints and the current state of technology are also considered. This white paper covers the following post-capture aspects of carbon sequestration: compression, transport, storage, and monitoring, mitigation and verification (MM+V). Read More

  • MPR Develops Reliability Centered Fleet Operation & Maintenance Budget Forecast

    The client desired improved unit reliability and power production to achieve management defined objectives when faced with changing expenditures to match corporate goals. Read More

  • Product Development White Paper: On-Line Monitoring and Process Analytical Technologies

    Process Analytical Technologies (PAT) are systems which provide continuous on-line monitoring of critical quality parameters and performance attributes of raw and in-process materials. Application of PATs to pharmaceutical manufacturing is an element of FDA's new risk-based approach to regulation described in "GMP's for the 21st Century." This document provides a brief overview of the approach being used to examine and implement PATs in the industry and discusses the roles that MPR can play in this effort. Read More

  • Reliability Improvement in the Hydrocarbon Process Industry

    Our client, a large United States based petrochemicals company, wanted to extend the interval between refinery compressor train maintenance outages from 8 to 10 years. Read More

  • Product Development White Paper: Risk-Based Validation of Computer Systems Used In FDA-Regulated Activities

    This document provides a summary of the requirements relating to use of computer-based systems in activities that are regulated by the FDA. The relevant FDA and industry guidance for complying with these requirements is also summarized. Finally, the approach proposed by MPR for system validation/qualification is discussed. The MPR approach uses risk-based prioritization to identify and address the most critical systems and functions first. For complex distributed systems, MPR's approach is to segment the system on a functional basis. This can be used, for example, to divide network systems into functional components that can then be prioritized based on risk and validated. Read More

  • MPR Re-powers NRG Long Beach Generation Facility Providing Critical Power to Southern California

    NRG Long Beach Generation Facility

    In December 2006, NRG initiated a $100 million emergency re-powering project to restore the Long Beach Generating Station to commercial operation. The specific objective was to re-power four of seven combustion turbines, which had been idled since 1998, prior to August 1, 2007 in order to meet the summer peak generation period. Read More

  • Hydrogen Production by Nuclear Heat: The Energy Carrier of the Future

    Research and development is constantly underway to create the next generation energy technology. It is impossible to know what the future holds, but future energy technology must be expandable, must be environmentally sound, must be effective and allow for expansion to improve the standard of living around the world, must be safe (both secure from outside threats and with a low risk to health and safety), and the energy technology must be economical. With these factors in mind, many believe that hydrogen is poised to be the next big revolution in the energy market. This paper considers several options for the production phase of this energy medium. The collection, transmission, and end-uses of hydrogen are not discussed. Specifically, the potential of three hydrogen production processes under development for the industrial production of hydrogen using nuclear energy are compared and evaluated. Read More